The APA actively supports research related to child health care delivery, children with special vulnerabilities, health promotion, and environmental health. Highlights from 2007 include CORNET (Continuity Research NETwork), the Pediatric Research in Inpatient Settings (PRIS) Network, and Young investigator Grants. CORNET has 77 pediatric training programs enrolled and includes 95 continuity practice sites. The number of CORNET training programs per APA region ranges from 3 to 12. The PRIS Network is a hospitalist research group formed through a collaborative effort of the APA, the AAP, and the Society of Hospital Medicine (SHM). The Young Investigator Grants supports the research of junior investigators; this year 47 applications were submitted and six were funded.

CORNET (Continuity Research NETwork) - Janet Serwint, MD
CORNET has had another productive year. Currently 77 pediatric training programs are enrolled that include 95 continuity practice sites. The number of training programs per APA region ranges from 3-12 programs. Our fifth manuscript has been accepted for publication:

Measuring primary care of children in pediatric resident continuity practices: A CORNET Study”, Scott D Krugman, Andrew Racine, Sharon Dabrow, Sandra Sanguino, W Meyer, M Seid, and Janet Serwint JR for the CORNET Investigators, Pediatrics, (in press).

Two additional manuscripts are in preparation from this study with Scott Krugman as the lead investigator, including “Identification of Primary Care Provider and Quality of Care” and “Quality of Care and Resident Level of Training”. All participating site investigators have the opportunity to participate as a co-author on one of the manuscripts providing they meet authorship requirements.

CORNET was well represented at the 2007 PAS meeting with a poster presentation and workshop. The poster entitled,” Hispanic patients receive high quality care in resident continuity practices, with authors Sott Krugman, Wendy L. Hobson, Lynn C. Garfunkel, Janet R. Serwint and Lilia Parra-Roide was presented on Sunday, 5/06/2007. Bill Stratbucker presented a workshop along with Janet R. Serwint, S. Feigelman, Susan D. Krugman, John Olsson, and Nui Dhepysawan entitled, “You CAN do Research within your Continuity Clinics: a CORNET Primer”, on May 8, 2007 from 8:30-11:30am. Several ideas for future CORNET projects were developed.

The Bright Futures Study” funded by the Maternal and Child Health Bureau is progressing well. Thirty-three pediatric training programs and over 270 pediatric residents have been recruited to participate in this randomized controlled trial that will evaluate an educational curriculum on Bright Futures concepts. The multi-center study requires IRB approval from all sites and recruitment of patients should begin this fall. The PI and Co-PI are Hank Bernstein and Janet Serwint.

CORNET is also collaborating with the PROS network of the AAP on the study, Secondary Sexual Characteristics in Boys (SSCIB). Nine CORNET practice sites have enrolled thus far. It is exciting to be collaborating with PROS on a study protocol and hope that this is the first of many future collaborations.

The 4th annual CORNET Meeting took place immediately after the PAS meeting in Toronto. We were fortunate to have Benard Dreyer as the APA Research Committee Chair join the CORNET Steering Committee. Upcoming projects that were discussed and approved by the CORNET Executive Committee include: a randomized controlled trial for application of fluoride varnish, a resident and preceptor survey concerning decision making about asthma treatment, and a randomized controlled trial to decrease aggression in early childhood.

The APA is in the third of a five-year agreement with the American Academy of Pediatrics to provide $15,000 annually for costs related to a meeting of the CORNET Advisory Committee. Janet Serwint is the principal investigator.

The APA continues in the second year of a four year grant from the Maternal and Child Health Research Program (MCHR) Targeted Issues to study the effects of the Bright Futures Guidelines for Health Supervision of Infants, Children and Adolescents on the quality of health promotion and preventive services delivered by pediatric residents in clinical outpatient settings. The award in the amount of $171,999 per year. Co-investigators are Janet Serwint and Hank Bernstein.

PRIS - Chris Landrigan, MD, MPH
The Pediatric Research in Inpatient Settings (PRIS) Network is a hospitalist research group that was formed through a collaborative effort of the APA, the AAP, and the Society of Hospital Medicine (SHM). Our mission is to improve the quality of care for hospitalized children by developing the evidence base for inpatient pediatric care. Over 80 hospitals and 200 hospitalists in the U.S. and Canada currently participate in PRIS. We welcome new participants and proposals for multi-center research projects both from hospitalists and from any clinical or health services researchers with an interest in the quality of hospital care. Further information, including details of how to submit a proposal, is available on the PRIS website – hosted by the APA – at http://www.ambpeds.org/site/research/research_PRIS.htm

Over the past 12 months, the level of activity in PRIS has greatly increased, spurred by our new Network Manager, Nui Dhepyasuwan, whose work with PRIS is being generously supported by the APA. Several projects have been proposed in the past 12 months, and are now in various stages of development:

  • We are currently in the process of surveying all members about their practice patterns, rounding styles, and involvement in sedation; (PRIS Triennial Survey: co-PIs: Chris Landrigan, Children’s Hospital Boston and Mary Ottolini, Children’s National Medical Center)
  • A study of complex pneumonia and parapneumoic effusion has been approved by PRIS and is being submitted to an external foundation for funding. This study plans to evaluate both the epidemiology of parapneumoic effusion in the post-pneumococcal vaccine era, and test the hypothesis that children treated with early VATS have improved outcomes compared with those managed expectantly (PI: Samir Shah, CHOP);
  • In collaboration with the Emergency Department network EMNet, we are planning a study of the inpatient management of children with bronchiolitis; R01 funding has been tentatively secured for this project (P.I. Carlos Camargo (EMNet/Massachusetts General Hospital); co-PI: Jonathan Mansbach (PRIS&EMNet/ Children’s Hospital Boston));
  • A study of the epidemiology of hospitalist inpatient practice is planned, using administrative data from across hospitalist services (PI: Jack Percelay, Hunterdon Medical Center)

We look forward to receiving additional study proposals, and launching our first multi-center studies this coming year. If you are interested in being a part of this network, or have a research proposal, please email Chris Landrigan at christopher.landrigan@childrens.harvard.edu and Nui Dhepyasuwan at nui@ambpeds.org.

Young investigator Grants - Benard Dreyer, MD
Process: The YIG Awards this year went through a multi-step process that the research committee oversaw.

  • Step 1: Announcement was sent out in September. 47 applications were submitted for the first part of the review process. The following were reviewers for the initial round: Benard Dreyer, Bill Cooper, Bob Jacobson, Bruce Lamphear, Danielle Laraque, David Wood, Denise Dougherty, Lee Pachter, Matt Davis, Michael Cabana, Peter Szilagyi, Shari Barkin, Scott Shipman, and Simon Hambidge. At least 5 reviewers were assigned to each of the abstracts. Peter Szilagyi re-designed the rating form for the first step of the review based on feedback from the Board. The first review process was completed by early November. Based on scoring of these abstracts, 18 proposals were invited to submit full proposals by December 15th.


  • Step 2: Assignment to “Regular APA” and AHRQ categories for second review was done by committee chair. 11 proposals were in the Regular APA group and 7 in the AHRQ group. $27,000 of funding was available from AHRQ, and $30-35,000 from the APA. Depending on scoring, 3-4 proposals were to be funded in each category.


  • Step 3: Second review. Two review committees were set up, one for the regular APA full proposals and one for the AHRQ full proposals. Reviewers for the regular APA full proposals included Peter Szilagyi, Michael Cabana, Shari Barkin, Scott Shipman, Michael Hambidge, and Benard Dreyer. Reviewers for the AHRQ full proposals included Bill Cooper, Bruce Lanphear, David Wood, Denise Dougherty, Michael Cabana, and Benard Dreyer. Each reviewer was a primary reviewer for one or two proposals and a secondary reviewer on another 1-2 proposals. Each reviewer read all proposals in the assigned group. Conference calls were scheduled for each group (APA, AHRQ) during which scores were shared, and consensus was reached on rank order. The top three proposals of in each category were proposed for funding. Because there was not a close score (a 4th proposal that scored very close to the 3rd ranking proposal), there was no discussion on either group of funding a 4th proposal and reducing funding for all proposals.


  • Step 4: notification. Letters of grant award or non-funding were sent all applicants, along with “pink sheets” compiled from detailed comments of primary and secondary reviewers, on March 12, 2006. Kelly Cooper greatly assisted in the entire process.

The following proposals were funded through the YIG process:

Investigator Institution Title of Proposal Amount Funder
Amanda Dempsey U. Michigan Evaluating risk fact-based strategies for HPV vaccination 10,000 APA
Helene Greves U. Washington Measuring the impact of school physical activity policies: can we identify best practices through behavior outcomes? 9,981 APA
Najah Musacchio Children’s Memorial / Northwestern Text message reminders to improve adolescent clinic attendance 8,700 APA
Srilakshmi Gnansekaran Harvard Medical School Child health policy and asthma: a multilevel analysis 9,200 AHRQ
Stephen Pont Vanderbilt U. Healthcare encounters due to diarrheal illness in children 9,953 AHRQ
Sheela Sathayanarayana U. Washington Is ambient air pollutant exposure associated with preterm and small for gestational age birth in the Puget Sound air basin? 9,996 AHRQ



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